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CoQ10 and the CoQ10 cycle play fundamental roles in the antioxidant and energy systems of the body. The ubiquinone form of CoQ10 is produced in the mitochondria, where it directly participates in energy production by accepting electrons in the electron transport chain. Through the action of an oxidoreductase enzyme, ubiquinone is rapidly converted to ubiquinol, the lipid- soluble form that supports antioxidant activity throughout the body. Conversion of ubiquinone to ubiquinol declines with age, particularly after age 40. Supplementation may help maintain normal levels of ubiquinol in the body as well as address drug-induced nutrient depletion of CoQ10. Until recently, the ubiquinol form had not been effective as a supplement because it was chemically unstable and easily oxidized. Bio-Q10™ contains a patented, absorbable form of ubiquinol that maintains its structure and stability in the gastrointestinal environment.
Antioxidant Status
Oxidative stress is detrimental to the integrity and function of cell membranes and tissues, and ultimately to DNA itself. Antioxidant status must be maintained throughout the body in order to protect vulnerable cells. Research indicates that ubiquinol supports antioxidant activity, including the regeneration of vitamins C and E, helping to maintain normal levels of free radical activity in the body. Researchers also suggest a possible role for CoQ10 in redox control of cell signaling and gene expression.
Cholesterol
Antioxidant protection is vital to maintaining the integrity of cholesterol and its role as a precursor to vitamin D, hormones, cell membranes, and brain tissue. Reactive oxygen species, including superoxide released by immune cells, cause the oxidation of cholesterol and can turn a vital biochemical precursor into a toxin.
CoQ10 Depletion
Serum CoQ10 levels decline with age but are also reduced with inhibition of the HMG-CoA reductase enzyme, an enzyme essential to CoQ10 production. In the event of reduced production, or drug-induced nutrient depletion, physicians recommend supplementation with CoQ10 to help maintain normal levels in the body. Related depletion of vitamin E in lymphocytes may raise further concerns about patients’ vulnerability to oxidative stress.
Heart Health
Research suggests that patients experienced significant support of cardiac function after receiving supplemental ubiquinol (an average 450-580 mg per day). These patients achieved more desirable levels of serum CoQ10 when switched from ubiquinone to ubiquinol. Researchers suggest that ubiquinol had dramatically improved absorption. Research on the elderly also appears to indicate that supplemental CoQ10 can increase tolerance to aerobic stress in cardiac tissue.
Kaneka QH™
Stabilized ubiquinol was developed by Kaneka Corporation (the world’s largest manufacturer of CoQ10) and was found to be safe and bioavailable following single and multiple doses.
Take one to two softgels daily, or as directed by your healthcare professional.
Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.
Medium-chain triglycerides, softgel (bovine gelatin, glycerin, purified water, and annatto in sunflower oil), ascorbyl palmitateS2, white beeswax, and sunflower lecithin.
Wheat, gluten, corn, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.
Keep closed in a cool, dry place out of reach of children.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.